γ-poly(L-glutamic acid) macromolecule
Poly(L-glutamate)
CAS: 25513-46-6
Molecular Formula: C5H9NO4
γ-poly(L-glutamic acid) macromolecule - Names and Identifiers
| Name | Poly(L-glutamate) |
| Synonyms | Poly(L-glutamate) glutamicacidpolymer alpha-l-glutamicacidpolymer Poly-γ-Glutamic Acid(γ-PGA) γ-poly(L-glutamic acid) macromolecule |
| CAS | 25513-46-6 |
| EINECS | 200-293-7 |
γ-poly(L-glutamic acid) macromolecule - Physico-chemical Properties
| Molecular Formula | C5H9NO4 |
| Molar Mass | 147.13 |
| Storage Condition | −20°C |
| Use | Uses Moisturizing, whitening, bacteriostatic and improving skin health. |
γ-poly(L-glutamic acid) macromolecule - Risk and Safety
| WGK Germany | 3 |
| RTECS | MA1700000 |
| FLUKA BRAND F CODES | 3-10 |
γ-poly(L-glutamic acid) macromolecule - Reference
| Reference Show more | 1. [IF=6.953] Zhiwei Su et al."Formation, characterization and application of arginine-modified chitosan/γ-poly glutamic acid nanoparticles as carrier for curcumin."Int J Biol Macromol. 2021 Jan;168:215 2. [IF=3.846] Yangfan Zheng et al."A new type of glutathione-responsive anti-osteosarcoma prodrug nanoparticles."Materials Technology. 2021 Apr 12 3. [IF=9.229] Ran Ye et al.Stable Loading and Delivery of Melittin with Lipid-Coated Polymeric Nanoparticles for Effective Tumor Therapy with Negligible Systemic Toxicity.Acs Appl Mater Inter. 2021;13(47):55902–55912 |
γ-poly(L-glutamic acid) macromolecule - Uses and synthesis methods
Definition of polyglutamic acid
polyglutamic acid (& gamma;-PGA), also known as natto gum, polyglutamic acid, it is a water-soluble, biodegradable, non-toxic, using microbial fermentation method to produce biopolymers. & gamma;-PGA polyglutamic acid is a sticky substance, first found in "natto"-fermented beans. & gamma;-PGA polyglutamic acid is a special anionic natural polymer, which is based on α-amine group (α -amino) and & gamma;-carboxyl group (& gamma; -caboxyl) is the same type polyamide (homo-polyamide)& gamma composed of amide linkage;-The molecular weight of PGA ranges from 50,000 to 2 million Daltons. Its moisturizing and water locking effect is 500 times that of hyaluronic acid. It is mainly used for moisturizing, whitening, inhibiting bacteria and improving skin health.
Polyglutamic acid was first found to exist in the high-viscosity wire drawing contained in Japanese natto food (fermented small soybeans). It is referred to as & gamma in China;-PGA, which uses natural Natto bacteria and glutamic acid through liquid fermentation for biological polymerization, resulting in a decomposable polymer of high molecular amino acid.
features
Non-toxic to the human body and the environment, biodegradable, eco-friendly;
Water-soluble, odorless, clean and transparent solution can be obtained;
Easy to cross-link to form a hydrogel with excellent performance in the later stage;
It can be made into sodium, calcium, magnesium, and hydrogen.
agricultural applications
& gamma;-polyglutamic acid & gamma;-PGA can be used as a nutrient for plant yield increase
1, & gamma;-polyglutamic acid & gamma;-PGA Hydrogel and & gamma;-PGA super hydrophilicity and water retention capacity
When flooded in the soil, a thin film will be formed on the surface of the root hair of the plant, which not only has the function of protecting the root hair, but also is the best transportation platform for the close contact of nutrients, water and root hair in the soil, which can be very effective Improve the dissolution, storage, transportation and absorption of fertilizer. Prevent sulfate, phosphate, oxalate and metal elements from precipitation, so that crops can more effectively absorb phosphorus, calcium, magnesium and trace elements in the soil. Promote the development of crop roots and strengthen disease resistance.
2, & gamma;-polyglutamic acid & gamma;-PGA Hydrogel and & gamma;-PGA equilibrium soil pH
It has excellent buffering capacity for acid and alkali, which can effectively balance the pH value of the soil and avoid the acid soil caused by long-term use of chemical fertilizers.
3, & gamma;-polyglutamic acid & gamma;-PGA Hydrogel and & gamma;-PGA can combine to precipitate toxic heavy metals
has excellent chelating effect on toxic heavy metals such as Pb +2, Cu +2, Cd +2, Cr +3, Al +3, As +4, etc.
4, & gamma;-polyglutamic acid & gamma;-PGA Hydrogel and & gamma;-PGA can enhance plant disease resistance and stress resistance
Integrating plant nutrients and water components in the soil can enhance resistance to symptoms caused by soil-borne plant pathogens.
5. Promote yield increase
it can rapidly increase production of agricultural products such as tea, fruits and vegetables, with an increase of 10-20%.
Polyglutamic acid is a homopolymer amino acid formed by connecting glutamic acid monomers through amide bonds. It has environmental friendliness, super chelation and adsorption capacity, super water absorption and moisture retention capacity and good biodegradation performance. The synergistic fertilizer added with polyglutamic acid has significant water retention, fertilizer retention, yield increase, stress resistance and improvement Five application effects of crop quality.
polyglutamic acid can be divided into two types: aqua and powder according to the content and different applicable fertilizer dosage forms. aqua can be divided into 1001-1007 seven types, and powder can be divided into 2001-2003 Three dosage forms, various dosage forms can be suitable for the production of chlorine-based, sulfur-based, urine-based, and nitro-based fertilizers, and are suitable for rollers, shotcreting, towers, and extrusion granulation!
Effect on skin
the main function of polyglutamic acid in cosmetics and skin care products is humectant and skin conditioner. the risk coefficient is 1, which is relatively safe and can be used with confidence. it generally has no effect on pregnant women, and polyglutamic acid has no acne.
Polyglutamic acid has a good promotion of the activity of fibroblast cells, and has a skin-activating effect. It can be used for anti-aging and anti-wrinkle cosmetics; polyglutamic acid with a larger molecular weight is not as good as the activity of fibroblast cells. Small molecular weight, but its performance in stabilizing foam, moisturizing ability, and adsorption on hair is better than small molecular weight products. It can be used in hair water and antistatic, soft hair 'polyglutamic acid has the effect of whitening skin.
Last Update：2024-04-09 21:04:16
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View History
γ-poly(L-glutamic acid) macromolecule
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C.I. Reactive Black 5
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